# Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/effect-of-kras-oncogene-substitutions-on-protein-behavior-implications-for/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Nathan T. Ihle,Lauren A. Byers,Edward S. Kim,Pierre Saintigny,J. Jack Lee,George R. Blumenschein,Anne S. Tsao,Suyu Liu,Jill E. Larsen,Jing Wang,Lixia Diao,Kevin R. Coombes,Lu Chen,Shuxing Zhang,Mena Abdelmelek,Ximing Tang,Vassiliki A. Papadimitrakopoulou,John D. Minna,Scott M. Lippman,Waun Ki Hong,Roy S. Herbst,Ignacio I. Wistuba,John V. Heymach,Garth Powis |
| Citations | 532 |
| DOI | 10.1093/jnci/djr523 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://academic.oup.com/jnci/article-pdf/104/3/228/17312088/djr523.pdf |
| OpenAlex ID | https://openalex.org/W2166923287 |
| PMID | 22247021 |
| Type | article |
| Year | 2012 |

## Paper authors

- [John V. Heymach](https://scholariq.org/researchers/john-v-heymach/)
- [Lauren A. Byers](https://scholariq.org/researchers/lauren-a-byers/)
- [George R. Blumenschein](https://scholariq.org/researchers/george-r-blumenschein/)
- [Jing Wang](https://scholariq.org/researchers/jing-wang-2/)
- [Garth Powis](https://scholariq.org/researchers/garth-powis/)

## Paper journal

- [JNCI Journal of the National Cancer Institute](https://scholariq.org/journals/jnci-journal-of-the-national-cancer-institute/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [Colorectal Cancer Treatments and Studies](https://scholariq.org/topics/colorectal-cancer-treatments-and-studies/)
- [Protein Kinase Regulation and GTPase Signaling](https://scholariq.org/topics/protein-kinase-regulation-and-gtpase-signaling/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.