# Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/effect-of-therapeutic-drug-monitoring-based-dose-optimization-of-piperacillin/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Stefan Hagel,Friedhelm Bach,Thorsten Brenner,Hendrik Bracht,Alexander Brinkmann,Thorsten Annecke,Andreas Höhn,Markus A. Weigand,Guido Michels,Stefan Kluge,Axel Nierhaus,Dominik Jarczak,Christina König,Dirk Weismann,Otto Frey,Dominic Witzke,Carsten Müller,Michael Bauer,Michael Kiehntopf,Sophie Neugebauer,Thomas Lehmann,Jason A. Roberts,Mathias W. Pletz,the TARGET Trial Investigators,Anke Braune,Karsten Schmidt,J. Motsch,Nadine Pinder,Daniel Richter,Peter Schlattmann,Andreas Ameln-Mayerhofer von,Markus Schappacher,Thomas Fuchs,Anka C. Röhr,Max Kurlbaum,Oliver Schreiner,Lars Hüter,Matthias Gründling,Stefan Angermair,Maria Deja,Frank Bloos,Sandra Fiedler,Hicham Chkirni |
| Citations | 176 |
| DOI | 10.1007/s00134-021-06609-6 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://link.springer.com/content/pdf/10.1007/s00134-021-06609-6.pdf |
| OpenAlex ID | https://openalex.org/W4210402439 |
| PMID | 35106617 |
| Type | article |
| Year | 2022 |

## Paper authors

- [Thorsten Annecke](https://scholariq.org/researchers/thorsten-annecke/)
- [Stefan Kluge](https://scholariq.org/researchers/stefan-kluge/)

## Paper journal

- [Intensive Care Medicine](https://scholariq.org/journals/intensive-care-medicine/)

## Paper primary topic

- [Sepsis Diagnosis and Treatment](https://scholariq.org/topics/sepsis-diagnosis-and-treatment/)

## Paper topics

- [Sepsis Diagnosis and Treatment](https://scholariq.org/topics/sepsis-diagnosis-and-treatment/)
- [Antibiotics Pharmacokinetics and Efficacy](https://scholariq.org/topics/antibiotics-pharmacokinetics-and-efficacy/)
- [Antibiotic Resistance in Bacteria](https://scholariq.org/topics/antibiotic-resistance-in-bacteria/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.