# Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/effect-of-treatment-delay-age-and-stroke-severity-on-the-effects-of-intravenous/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jonathan Emberson,Kennedy R. Lees,Patrick D. Lyden,Lisa Blackwell,Gregory W. Albers,Erich Bluhmki,Thomas Brott,Geoff Cohen,Stephen C. Davis,Geoffrey A. Donnan,James C. Grotta,George Howard,Markku Kaste,Masatoshi Koga,Ruediger von Kummer,Maarten G. Lansberg,Richard I. Lindley,Gordon Murray,Jean‐Marc Olivot,Mark Parsons,Barbara C. Tilley,Danilo Toni,Ḱazunori Toyoda,Nils Wahlgren,Joanna M. Wardlaw,William Whiteley,Gregory J. del Zoppo,Colin Baigent,Peter Sandercock,Werner Hacke |
| Citations | 2,753 |
| DOI | 10.1016/s0140-6736(14)60584-5 |
| Fields | Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | http://www.thelancet.com/article/S0140673614605845/pdf |
| OpenAlex ID | https://openalex.org/W2165568749 |
| PMID | 25106063 |
| Type | review |
| Year | 2014 |

## Paper authors

- [Joanna M. Wardlaw](https://scholariq.org/researchers/joanna-m-wardlaw/)

## Paper journal

- [The Lancet](https://scholariq.org/journals/the-lancet/)

## Paper primary topic

- [Acute Ischemic Stroke Management](https://scholariq.org/topics/acute-ischemic-stroke-management/)

## Paper topics

- [Acute Ischemic Stroke Management](https://scholariq.org/topics/acute-ischemic-stroke-management/)
- [Intracerebral and Subarachnoid Hemorrhage Research](https://scholariq.org/topics/intracerebral-and-subarachnoid-hemorrhage-research/)
- [Stroke Rehabilitation and Recovery](https://scholariq.org/topics/stroke-rehabilitation-and-recovery/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
