# Effectiveness of oral step-down therapy and early oral switch for bloodstream infections caused by Enterobacterales: A post hoc emulation trial of the SIMPLIFY trial

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/effectiveness-of-oral-step-down-therapy-and-early-oral-switch-for-bloodstream/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Emanuele Rando,Mercedes Delgado-Valverde,Josune Goikoetxea Aguirre,Laura Guío Carrión,María José Blanco Vidal,José Andrés,María Teresa Pérez Rodríguez,Lucía Martínez Lamas,Francisco Arnaíz de las Revillas,Carlos Armiñanzas,Carlos Ruiz de Alegría Puig,Patricia Jiménez Aguilar,María del Carmen Martínez-Rubio,Carmen Sáez-Béjar,Carmen de las Cuevas,Andrés Martín-Aspas,Fátima Galán‐Sánchez,José Ramón Yuste,José Leiva,Germán Bou,Patricia Capón González,Lucía Boix-Palop,Mariona Xercavins-Valls,Miguel Ángel Goenaga-Sánchez,Diego Vicente Anza,Juan José Castón,Manuel Recio,Esperanza Merino,Juan Carlos Rodrı́guez,Belén Loeches,Clara Rosso-Fernández,José María Bravo-Ferrer,Pilar Retamar,Jesús Rodríguez‐Baño,Luis Eduardo López-Cortés |
| Citations | 3 |
| DOI | 10.1016/j.ijid.2025.107917 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | gold |
| OA URL | https://www.ijidonline.com/article/S1201-9712(25)00140-7/pdf |
| OpenAlex ID | https://openalex.org/W4409920963 |
| PMID | 40311800 |
| Type | article |
| Year | 2025 |

## Paper authors

- [Esperanza Merino](https://scholariq.org/researchers/esperanza-merino/)
- [Jesús Rodríguez‐Baño](https://scholariq.org/researchers/jesus-rodriguez-bano/)
- [Germán Bou](https://scholariq.org/researchers/german-bou/)
- [Juan Carlos Rodrı́guez](https://scholariq.org/researchers/juan-carlos-rodr-guez/)
- [Luis Eduardo López-Cortés](https://scholariq.org/researchers/luis-eduardo-lopez-cortes/)

## Paper funders

- [Ministerio de Ciencia, Innovación y Universidades](https://scholariq.org/funders/ministerio-de-ciencia-innovacion-y-universidades/)
- [European Commission](https://scholariq.org/funders/european-commission/)
- [Instituto de Salud Carlos III](https://scholariq.org/funders/instituto-de-salud-carlos-iii/)
- [European Regional Development Fund](https://scholariq.org/funders/european-regional-development-fund/)

## Paper journal

- [International Journal of Infectious Diseases](https://scholariq.org/journals/international-journal-of-infectious-diseases/)

## Paper primary topic

- [Antibiotic Resistance in Bacteria](https://scholariq.org/topics/antibiotic-resistance-in-bacteria/)

## Paper topics

- [Antibiotic Resistance in Bacteria](https://scholariq.org/topics/antibiotic-resistance-in-bacteria/)
- [Antibiotics Pharmacokinetics and Efficacy](https://scholariq.org/topics/antibiotics-pharmacokinetics-and-efficacy/)
- [Antibiotic Use and Resistance](https://scholariq.org/topics/antibiotic-use-and-resistance/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.