# Efficacy and Safety of Early Initiation of Eplerenone Treatment in Patients with Acute Heart Failure (EARLIER trial): a multicentre, randomized, double-blind, placebo-controlled trial

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/efficacy-and-safety-of-early-initiation-of-eplerenone-treatment-in-patients-with/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Masanori Asakura,Shin Ito,Takahisa Yamada,Yoshihiko Saito,Kazuo Kimura,Akira Yamashina,Atsushi Hirayama,Youichi Kobayashi,Akihisa Hanatani,Mitsuru Tsujimoto,Satoshi Yasuda,Yukio Abe,Yorihiko Higashino,Yodo Tamaki,Hiroshi Sugino,Hiroyuki Niinuma,Yoshitaka Okuhara,Toshimi Koitabashi,Shin‐ichi Momomura,Kuniya Asai,Akihiro Nomura,Hiroya Kawai,Yasuhiro Satoh,Tsutomu Yoshikawa,Ken–ichi Hirata,Yoshiaki Yokoi,Jun Tanaka,Yoshisato Shibata,Yasuhiro Maejima,Shunsuke Tamaki,Hiroyuki Kawata,Noriaki Iwahashi,Masatake Kobayashi,Yoshiharu Higuchi,Akiko Kada,Haruko Yamamoto,Masafumi Kitakaze |
| Citations | 42 |
| DOI | 10.1093/ehjcvp/pvaa132 |
| Fields | Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W3099281063 |
| PMID | 33175088 |
| Type | article |
| Year | 2020 |

## Paper authors

- [Masatake Kobayashi](https://scholariq.org/researchers/masatake-kobayashi/)
- [Shin Ito](https://scholariq.org/researchers/shin-ito/)

## Paper journal

- [European Heart Journal - Cardiovascular Pharmacotherapy](https://scholariq.org/journals/european-heart-journal-cardiovascular-pharmacotherapy/)

## Paper primary topic

- [Hormonal Regulation and Hypertension](https://scholariq.org/topics/hormonal-regulation-and-hypertension/)

## Paper topics

- [Hormonal Regulation and Hypertension](https://scholariq.org/topics/hormonal-regulation-and-hypertension/)
- [Heart Failure Treatment and Management](https://scholariq.org/topics/heart-failure-treatment-and-management/)
- [Adrenal Hormones and Disorders](https://scholariq.org/topics/adrenal-hormones-and-disorders/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.