# Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray Combined With a Newly Initiated Oral Antidepressant in Treatment-Resistant Depression: A Randomized Double-Blind Active-Controlled Study

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/efficacy-and-safety-of-flexibly-dosed-esketamine-nasal-spray-combined-with-a/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Vanina Popova,Ella Daly,Madhukar H. Trivedi,Kimberly Cooper,Rosanne Lane,Pilar Lim,Christine Mazzucco,David Hough,Michael E. Thase,Richard C. Shelton,Patricio Molero,Eduard Vieta,Malek Bajbouj,Husseini K. Manji,Wayne C. Drevets,Jaskaran Singh |
| Citations | 886 |
| DOI | 10.1176/appi.ajp.2019.19020172 |
| Fields | Medicine,Psychology |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2019.19020172 |
| OpenAlex ID | https://openalex.org/W2946661342 |
| PMID | 31109201 |
| Type | article |
| Year | 2019 |

## Paper authors

- [Wayne C. Drevets](https://scholariq.org/researchers/wayne-c-drevets/)
- [Eduard Vieta](https://scholariq.org/researchers/eduard-vieta/)
- [Kimberly Cooper](https://scholariq.org/researchers/kimberly-cooper/)
- [Rosanne Lane](https://scholariq.org/researchers/rosanne-lane/)
- [Jaskaran Singh](https://scholariq.org/researchers/jaskaran-singh/)

## Paper primary topic

- [Treatment of Major Depression](https://scholariq.org/topics/treatment-of-major-depression/)

## Paper topics

- [Treatment of Major Depression](https://scholariq.org/topics/treatment-of-major-depression/)
- [Psychedelics and Drug Studies](https://scholariq.org/topics/psychedelics-and-drug-studies/)
- [Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes](https://scholariq.org/topics/anxiety-depression-psychometrics-treatment-cognitive-processes/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.