# Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/efficacy-and-safety-of-low-dose-il-2-as-an-add-on-therapy-to-riluzole-mirocals-a/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Gilbert Bensimon,P. Nigel Leigh,Timothy Tree,Andrea Malaspina,Christine Payan,Hang‐Phuong Pham,Pieter Klaassen,Pamela J. Shaw,Ahmad Al Khleifat,Maria del Mar Amador,Shahram Attarian,Simon Bell,S. Beltran,Emilien Bernard,William Camu,Philippe Corcia,Jean-Christophe Corvol,Philippe Couratier,Véronique Danel,Rabab Debs,Claude Desnuelle,Aikaterini Dimitriou,John Ealing,Florence Esselin,Marie‐Céline Fleury,George Gorrie,Aude-Marie Grapperon,Adèle Hesters,Raúl Juntas‐Morales,Ivan Kolev,Géraldine Lautrette,Nadine Le Forestier,Christopher McDermott,Nicolas Pageot,François Salachas,Nikhil Sharma,Marie-Hélène Soriani,Jemeen Sreedharan,Juliette Svahn,Nick Verber,Annie Verschueren,Özlem Yildiz,Carey Suehs,Safaa Saker-Delye,C Müller,Christophe Masseguin,Hana Hajduchová,Janine Kirby,Cecília Garlanda,Massimo Locati,Henrik Zetterberg,Bernard Asselain,Ammar Al‐Chalabi |
| Citations | 34 |
| DOI | 10.1016/s0140-6736(25)00262-4 |
| Fields | Medicine,Neuroscience |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://www.thelancet.com/action/showPdf?pii=S0140673625002624 |
| OpenAlex ID | https://openalex.org/W4410222111 |
| PMID | 40354799 |
| Type | article |
| Year | 2025 |

## Paper authors

- [Adèle Hesters](https://scholariq.org/researchers/adele-hesters/)

## Paper journal

- [The Lancet](https://scholariq.org/journals/the-lancet/)

## Paper primary topic

- [Amyotrophic Lateral Sclerosis Research](https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/)

## Paper topics

- [Amyotrophic Lateral Sclerosis Research](https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/)
- [Multiple Sclerosis Research Studies](https://scholariq.org/topics/multiple-sclerosis-research-studies/)
- [Genetic Neurodegenerative Diseases](https://scholariq.org/topics/genetic-neurodegenerative-diseases/)

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