# Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/efficacy-and-safety-of-setmelanotide-an-mc4r-agonist-in-individuals-with-severe/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Karine Clément,Erica L T van den Akker,Jesús Argente,Allison Bahm,Wendy K Chung,Hillori Connors,Kathleen De Waele,I. Sadaf Farooqi,Julie Gonneau-Lejeune,Gregory Gordon,Katja Kohlsdorf,Christine Poitou,Lia Puder,James Swain,Murray Stewart,Guojun Yuan,Martin Wabitsch,Peter Kühnen,Patricia Pigeon-Kherchiche,Anna Flaus-Furmaniuk,Martin Bald,Christian Denzer,Julia von Schnurbein,Ozair Abawi,Ulrike Blume‐Peytavi,Philipp Krabusch,Knut Mai,Dirk Schnabel,Susanna Wiegand,Christa E. Flück,Esther Schulz,Egbert Voß,Nataša Bratina,Katja Weiß,Gabriel Ángel Martos‐Moreno,Alban Danset,Paul Gougis,Béatrice Dubern,Karine Clément,Erica L T van den Akker,Jesús Argente,Allison Bahm,Wendy K Chung,Hillori Connors,Kathleen De Waele,I. Sadaf Farooqi,Julie Gonneau-Lejeune,Gregory Gordon,Christine Poitou,Lia Puder,James Swain,Murray Stewart,Goujun Yuan,Martin Wabitsch,Peter Kühnen |
| Citations | 472 |
| DOI | 10.1016/s2213-8587(20)30364-8 |
| Fields | Medicine,Neuroscience,Nursing |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W3095455148 |
| PMID | 33137293 |
| Type | article |
| Year | 2020 |

## Paper authors

- [Murray Stewart](https://scholariq.org/researchers/murray-stewart/)

## Paper journal

- [The Lancet Diabetes & Endocrinology](https://scholariq.org/journals/the-lancet-diabetes-and-endocrinology/)

## Paper primary topic

- [Regulation of Appetite and Obesity](https://scholariq.org/topics/regulation-of-appetite-and-obesity/)

## Paper topics

- [Regulation of Appetite and Obesity](https://scholariq.org/topics/regulation-of-appetite-and-obesity/)
- [Adipokines, Inflammation, and Metabolic Diseases](https://scholariq.org/topics/adipokines-inflammation-and-metabolic-diseases/)
- [Biochemical Analysis and Sensing Techniques](https://scholariq.org/topics/biochemical-analysis-and-sensing-techniques/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.