# Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/estradiol-downregulates-mir-21-expression-and-increases-mir-21-target-gene/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Nalinie S. Wickramasinghe,Tissa T. Manavalan,Susan Dougherty,Krista A. Riggs,Yong Li,Carolyn M. Klinge |
| Citations | 396 |
| DOI | 10.1093/nar/gkp117 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | true |
| OA Status | gold |
| OA URL | https://academic.oup.com/nar/article-pdf/37/8/2584/16757490/gkp117.pdf |
| OpenAlex ID | https://openalex.org/W2130018512 |
| PMID | 19264808 |
| Type | article |
| Year | 2009 |

## Paper authors

- [Yong Li](https://scholariq.org/researchers/yong-li/)

## Paper primary topic

- [MicroRNA in disease regulation](https://scholariq.org/topics/microrna-in-disease-regulation/)

## Paper topics

- [MicroRNA in disease regulation](https://scholariq.org/topics/microrna-in-disease-regulation/)
- [Cancer-related molecular mechanisms research](https://scholariq.org/topics/cancer-related-molecular-mechanisms-research/)
- [RNA Research and Splicing](https://scholariq.org/topics/rna-research-and-splicing/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.