# Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/evaluation-of-tcr-gene-editing-achieved-by-talens-crispr-cas9-and-megatal/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Mark J. Osborn,Beau R. Webber,Friederike Knipping,Cara-lin Lonetree,Nicole Tennis,Anthony P. DeFeo,Amber McElroy,Colby G. Starker,Catherine Lee,Sarah C. Merkel,Troy C. Lund,Karen S. Kelly‐Spratt,Michael C. Jensen,Daniel F. Voytas,Christof von Kalle,Manfred Schmidt,Richard Gabriel,Keli L. Hippen,Jeffrey S. Miller,Andrew M. Scharenberg,Jakub Tolar,Bruce R. Blazar |
| Citations | 201 |
| DOI | 10.1038/mt.2015.197 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | http://www.cell.com/article/S1525001616309753/pdf |
| OpenAlex ID | https://openalex.org/W2247762492 |
| PMID | 26502778 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Beau R. Webber](https://scholariq.org/researchers/beau-r-webber/)

## Paper primary topic

- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)

## Paper topics

- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)
- [CRISPR and Genetic Engineering](https://scholariq.org/topics/crispr-and-genetic-engineering/)
- [Virus-based gene therapy research](https://scholariq.org/topics/virus-based-gene-therapy-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.