# Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/excessive-mechanical-loading-promotes-osteoarthritis-through-the-gremlin-1-nf-b/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Song Ho Chang,Daisuke Mori,Hiroshi Kobayashi,Yoshifumi Mori,Hideki Nakamoto,Keita Okada,Yuki Taniguchi,Shurei Sugita,Fumiko Yano,Ung‐il Chung,Joo‐ri Kim‐Kaneyama,Motoko Yanagita,Aris N. Economides,Ernesto Canalis,Di Chen,Sakae Tanaka,Taku Saito |
| Citations | 296 |
| DOI | 10.1038/s41467-019-09491-5 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | gold |
| OA URL | https://www.nature.com/articles/s41467-019-09491-5.pdf |
| OpenAlex ID | https://openalex.org/W2931313255 |
| PMID | 30926814 |
| Type | article |
| Year | 2019 |

## Paper authors

- [Motoko Yanagita](https://scholariq.org/researchers/motoko-yanagita/)

## Paper journal

- [Nature Communications](https://scholariq.org/journals/nature-communications/)

## Paper primary topic

- [Bone Metabolism and Diseases](https://scholariq.org/topics/bone-metabolism-and-diseases/)

## Paper topics

- [Bone Metabolism and Diseases](https://scholariq.org/topics/bone-metabolism-and-diseases/)
- [NF-κB Signaling Pathways](https://scholariq.org/topics/nf-b-signaling-pathways/)
- [Inflammatory mediators and NSAID effects](https://scholariq.org/topics/inflammatory-mediators-and-nsaid-effects/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.