# First-in-Human, Phase I Dose-Escalation and Dose-Expansion Study of Trophoblast Cell-Surface Antigen 2–Directed Antibody-Drug Conjugate Datopotamab Deruxtecan in Non–Small-Cell Lung Cancer: TROPION-PanTumor01

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/first-in-human-phase-i-dose-escalation-and-dose-expansion-study-of-trophoblast/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Toshio Shimizu,Jacob Sands,Kiyotaka Yoh,Alexander I. Spira,Edward B. Garon,Satoru Kitazono,Melissa L. Johnson,Funda Meric‐Bernstam,Anthony W. Tolcher,Noboru Yamamoto,Jon Greenberg,Yui Kawasaki,Hong Zebger‐Gong,Fumiaki Kobayashi,Penny Phillips,Aaron Lisberg,Rebecca S. Heist |
| Citations | 178 |
| DOI | 10.1200/jco.23.00059 |
| Fields | Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://ascopubs.org/doi/pdfdirect/10.1200/JCO.23.00059?role=tab |
| OpenAlex ID | https://openalex.org/W4380881366 |
| PMID | 37327461 |
| Type | article |
| Year | 2023 |

## Paper authors

- [Edward B. Garon](https://scholariq.org/researchers/edward-b-garon/)
- [Aaron Lisberg](https://scholariq.org/researchers/aaron-lisberg/)
- [Rebecca S. Heist](https://scholariq.org/researchers/rebecca-s-heist/)

## Paper journal

- [Journal of Clinical Oncology](https://scholariq.org/journals/journal-of-clinical-oncology/)

## Paper primary topic

- [HER2/EGFR in Cancer Research](https://scholariq.org/topics/her2-egfr-in-cancer-research/)

## Paper topics

- [HER2/EGFR in Cancer Research](https://scholariq.org/topics/her2-egfr-in-cancer-research/)
- [Lung Cancer Research Studies](https://scholariq.org/topics/lung-cancer-research-studies/)
- [Peptidase Inhibition and Analysis](https://scholariq.org/topics/peptidase-inhibition-and-analysis/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.