# FOLFIRI (folinic acid, fluorouracil, and irinotecan) increases not efficacy but toxicity compared with single-agent irinotecan as a second-line treatment in metastatic colorectal cancer patients: a randomized clinical trial

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/folfiri-folinic-acid-fluorouracil-and-irinotecan-increases-not-efficacy-but/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Xiaowei Zhang,Ran Duan,Yusheng Wang,Xin Liu,Wen Zhang,Xiaodong Zhu,Zhiyu Chen,Wei Feng Shen,Yifu He,Hongqiang Wang,Mingzhu Huang,Chenchen Wang,Zhe Zhang,Xiaoying Zhao,Li‐Xin Qiu,Jianfeng Luo,Xuedan Sheng,Weijian Guo |
| Citations | 26 |
| DOI | 10.1177/17588359211068737 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | gold |
| OA URL | https://doi.org/10.1177/17588359211068737 |
| OpenAlex ID | https://openalex.org/W4205266052 |
| PMID | 35069808 |
| Type | article |
| Year | 2022 |

## Paper authors

- [Ran Duan](https://scholariq.org/researchers/ran-duan/)

## Paper primary topic

- [Colorectal Cancer Treatments and Studies](https://scholariq.org/topics/colorectal-cancer-treatments-and-studies/)

## Paper topics

- [Colorectal Cancer Treatments and Studies](https://scholariq.org/topics/colorectal-cancer-treatments-and-studies/)
- [Cancer therapeutics and mechanisms](https://scholariq.org/topics/cancer-therapeutics-and-mechanisms/)
- [Colorectal Cancer Surgical Treatments](https://scholariq.org/topics/colorectal-cancer-surgical-treatments/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.