# FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/fxr-inhibition-may-protect-from-sars-cov-2-infection-by-reducing-ace2/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Teresa Brevini,Mailis Maes,Gwilym J. Webb,Binu V. John,Claudia Fuchs,Gustav Buescher,Lu Wang,C. Griffiths,Marnie L. Brown,William E. Scott,Pehuén Pereyra-Gerber,William Gelson,Stephanie Brown,Scott Dillon,Daniele Muraro,Joanne Sharp,Megan Neary,Helen Box,Lee Tatham,James P. Stewart,Paul Curley,Henry Pertinez,Sally Forrest,Petra Mlčochová,Sagar Varankar,Mahnaz Darvish-Damavandi,Victoria Mulcahy,Rhoda E. Kuc,Thomas Williams,James A. Heslop,Davide Rossetti,Olivia Tysoe,Vasileios Galanakis,Marta Vilà‐González,Thomas W. M. Crozier,Johannes Bargehr,Sanjay Sinha,Sara Upponi,Corrina Fear,Lisa Swift,Kourosh Saeb‐Parsy,Susan Davies,Axel Wester,Hannes Hagström,Espen Melum,Darran Clements,Peter Humphreys,Jo Herriott,Edyta Kijak,Helen Cox,Chloe Bramwell,Anthony Valentijn,Christopher J. R. Illingworth,Bassam Dahman,Dustin Bastaich,Raphaella Ferreira,Thomas Marjot,Eleanor Barnes,Andrew M. Moon,A. Sidney Barritt,Ravindra K. Gupta,Stephen Baker,Anthony P. Davenport,Gareth Corbett,Vassilis G. Gorgoulis,Simon J. A. Buczacki,Joo‐Hyeon Lee,Nicholas J. Matheson,Michael Trauner,Andrew J. Fisher,Paul Gibbs,Andrew J. Butler,Christopher J.E. Watson,George Mells,Gordon Dougan,Andrew Owen,Ansgar W. Lohse,Ludovic Vallier,Fotios Sampaziotis |
| Citations | 299 |
| DOI | 10.1038/s41586-022-05594-0 |
| Fields | Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://www.nature.com/articles/s41586-022-05594-0.pdf |
| OpenAlex ID | https://openalex.org/W4310774393 |
| PMID | 36470304 |
| Type | article |
| Year | 2022 |

## Paper authors

- [William E. Scott](https://scholariq.org/researchers/william-e-scott/)
- [Christopher J.E. Watson](https://scholariq.org/researchers/christopher-j-e-watson/)
- [Kourosh Saeb‐Parsy](https://scholariq.org/researchers/kourosh-saeb-parsy/)

## Paper journal

- [Nature](https://scholariq.org/journals/nature/)

## Paper primary topic

- [SARS-CoV-2 and COVID-19 Research](https://scholariq.org/topics/sars-cov-2-and-covid-19-research/)

## Paper topics

- [SARS-CoV-2 and COVID-19 Research](https://scholariq.org/topics/sars-cov-2-and-covid-19-research/)
- [Drug Transport and Resistance Mechanisms](https://scholariq.org/topics/drug-transport-and-resistance-mechanisms/)
- [Immunotherapy and Immune Responses](https://scholariq.org/topics/immunotherapy-and-immune-responses/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.