# Genome-wide study of DNA methylation in Amyotrophic Lateral Sclerosis identifies differentially methylated loci and implicates metabolic, inflammatory and cholesterol pathways

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/genome-wide-study-of-dna-methylation-in-amyotrophic-lateral-sclerosis-identifies/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Paul J. Hop,Ramona A.J. Zwamborn,Eilís Hannon,Gemma Shireby,Marta F. Nabais,Emma Walker,Wouter van Rheenen,Joke J.F.A. van Vugt,Annelot M. Dekker,Henk‐Jan Westeneng,Gijs H.P. Tazelaar,Kristel R. van Eijk,Matthieu Moisse,Denis Baird,Ahmad Al Khleifat,Alfredo Iacoangeli,Nicola Ticozzi,Antonia Ratti,Johnathan Cooper‐Knock,Karen Morrison,Pamela J. Shaw,A. Nazlı Başak,Adriano Chiò,Andrea Calvo,Cristina Moglia,Antonio Canosa,Maura Brunetti,Maurizio Grassano,Marc Gotkine,Yossef Lerner,Michal Zabari,Patrick Vourc’h,Philippe Corcia,P. Couratier,Jesús S. Mora Pardina,Teresa Salas,Patrick A. Dion,Jay P. Ross,Robert D. Henderson,Susan Mathers,Pamela McCombe,Merrilee Needham,Garth A. Nicholson,Dominic B. Rowe,Roger Pamphlett,Karen A. Mather,Perminder S. Sachdev,Sarah Furlong,Fleur C. Garton,Anjali K. Henders,Tian Lin,Shyuan T. Ngo,Frederik J. Steyn,Leanne Wallace,Kelly L. Williams,Miguel Mitne‐Neto,Ruben J. Cauchi,Ian P. Blair,Matthew C. Kiernan,Vivian E. Drory,Mónica Povedano,Mamede de Carvalho,Susana Pinto,Markus Weber,Guy A. Rouleau,Vincenzo Silani,John E. Landers,Christopher E. Shaw,Peter M. Andersen,Allan F. McRae,Michael A. van Es,R. Jeroen Pasterkamp,Naomi R. Wray,Russell L. McLaughlin,Orla Hardiman,Kevin P. Kenna,Ellen Tsai,Heiko Runz,Ammar Al‐Chalabi,Leonard H. van den Berg,Philip Van Damme,Jonathan Mill,Jan H. Veldink |
| Citations | 8 |
| DOI | 10.1101/2021.03.12.21253115 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.medrxiv.org/content/medrxiv/early/2021/03/24/2021.03.12.21253115.full.pdf |
| OpenAlex ID | https://openalex.org/W3137053129 |
| Type | preprint |
| Year | 2021 |

## Paper authors

- [P. Couratier](https://scholariq.org/researchers/p-couratier/)

## Paper journal

- [medRxiv](https://scholariq.org/journals/medrxiv/)

## Paper primary topic

- [Amyotrophic Lateral Sclerosis Research](https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/)

## Paper topics

- [Amyotrophic Lateral Sclerosis Research](https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/)
- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)
- [Cancer-related gene regulation](https://scholariq.org/topics/cancer-related-gene-regulation/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.