# Heterogeneity Underlies the Emergence of <i>EGFR</i> T790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/heterogeneity-underlies-the-emergence-of-i-egfr-i-t790-wild-type-clones/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Zofia Piotrowska,Matthew J. Niederst,Chris Karlovich,Heather A. Wakelee,Joel W. Neal,Mari Mino–Kenudson,Linnea Fulton,Aaron N. Hata,Elizabeth L. Lockerman,Anuj Kalsy,Subba R. Digumarthy,Alona Muzikansky,Mitch Raponi,Angel R. Garcia,Hillary E. Mulvey,Melissa Parks,Richard H. DiCecca,Dora Dias‐Santagata,A. John Iafrate,Alice T. Shaw,Andrew R. Allen,Jeffrey A. Engelman,Lecia V. Sequist |
| Citations | 461 |
| DOI | 10.1158/2159-8290.cd-15-0399 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/4497836 |
| OpenAlex ID | https://openalex.org/W2065293650 |
| PMID | 25934077 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Zofia Piotrowska](https://scholariq.org/researchers/zofia-piotrowska/)
- [A. John Iafrate](https://scholariq.org/researchers/a-john-iafrate/)
- [Alona Muzikansky](https://scholariq.org/researchers/alona-muzikansky/)
- [Heather A. Wakelee](https://scholariq.org/researchers/heather-a-wakelee/)
- [Jeffrey A. Engelman](https://scholariq.org/researchers/jeffrey-a-engelman/)
- [Mari Mino–Kenudson](https://scholariq.org/researchers/mari-mino-kenudson/)
- [Alice T. Shaw](https://scholariq.org/researchers/alice-t-shaw/)
- [Aaron N. Hata](https://scholariq.org/researchers/aaron-n-hata/)
- [Lecia V. Sequist](https://scholariq.org/researchers/lecia-v-sequist/)

## Paper funders

- [National Cancer Institute](https://scholariq.org/funders/national-cancer-institute/)

## Paper journal

- [Cancer Discovery](https://scholariq.org/journals/cancer-discovery/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [Lung Cancer Research Studies](https://scholariq.org/topics/lung-cancer-research-studies/)
- [Cancer Genomics and Diagnostics](https://scholariq.org/topics/cancer-genomics-and-diagnostics/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.