# Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/highly-selective-inhibition-of-tyrosine-kinase-2-tyk2-for-the-treatment-of/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Stephen T. Wrobleski,Ryan Moslin,Shuqun Lin,Yanlei Zhang,Steven H. Spergel,James Kempson,John S. Tokarski,Joann Strnad,Adriana Zupa-Fernandez,Lihong Cheng,David J. Shuster,Kathleen M. Gillooly,Xiaoxia Yang,Elizabeth Heimrich,Kim W. McIntyre,Charu Chaudhry,Javed Khan,Max Ruzanov,Jeffrey Tredup,Dawn Mulligan,Dianlin Xie,Huadong Sun,Christine Huang,Celia D’Arienzo,Nelly Aranı́bar,Manoj Chiney,Anjaneya Chimalakonda,William J. Pitts,Louis J. Lombardo,Percy H. Carter,James R. Burke,David S. Weinstein |
| Citations | 378 |
| DOI | 10.1021/acs.jmedchem.9b00444 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q2930xjs |
| OpenAlex ID | https://openalex.org/W2956179332 |
| PMID | 31318208 |
| Type | article |
| Year | 2019 |

## Paper authors

- [Xiaoxia Yang](https://scholariq.org/researchers/xiaoxia-yang/)

## Paper primary topic

- [Cytokine Signaling Pathways and Interactions](https://scholariq.org/topics/cytokine-signaling-pathways-and-interactions/)

## Paper topics

- [Cytokine Signaling Pathways and Interactions](https://scholariq.org/topics/cytokine-signaling-pathways-and-interactions/)
- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)
- [Chronic Lymphocytic Leukemia Research](https://scholariq.org/topics/chronic-lymphocytic-leukemia-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.