# Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/hypoxia-induces-hif1-dependent-epigenetic-vulnerability-in-triple-negative/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Shijun Ma,Yue Zhao,Wee Chyan Lee,L.S. Ong,Puay Leng Lee,Zemin Jiang,Gokce Oguz,Zhitong Niu,Min Liu,Jian Yuan Goh,Wenyu Wang,Matías A. Bustos,Sidse Ehmsen,Adaikalavan Ramasamy,Dave S.�B. Hoon,Henrik J. Ditzel,Ern Yu Tan,Qingfeng Chen,Qiang Yu |
| Citations | 183 |
| DOI | 10.1038/s41467-022-31764-9 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | gold |
| OA URL | https://www.nature.com/articles/s41467-022-31764-9.pdf |
| OpenAlex ID | https://openalex.org/W4285493755 |
| PMID | 35840558 |
| Type | article |
| Year | 2022 |

## Paper authors

- [Min Liu](https://scholariq.org/researchers/min-liu-2/)
- [Yue Zhao](https://scholariq.org/researchers/yue-zhao/)

## Paper journal

- [Nature Communications](https://scholariq.org/journals/nature-communications/)

## Paper primary topic

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)

## Paper topics

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)
- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)
- [Cancer Immunotherapy and Biomarkers](https://scholariq.org/topics/cancer-immunotherapy-and-biomarkers/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.