# Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/hypoxic-tumor-microenvironment-activates-gli2-via-hif-1-and-tgf-2-to-promote/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Yen-An Tang,Yu-feng Chen,Bao Yi,Sylvia Mahara,Siti Maryam J. M. Yatim,Gokce Oguz,Puay Leng Lee,Min Feng,Yu Cai,Ern Yu Tan,Sau Shung Fong,Zi-huan Yang,Ping Lan,Xiaojian Wu,Qiang Yu |
| Citations | 277 |
| DOI | 10.1073/pnas.1801348115 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://www.pnas.org/content/pnas/115/26/E5990.full.pdf |
| OpenAlex ID | https://openalex.org/W2808190774 |
| PMID | 29891662 |
| Type | article |
| Year | 2018 |

## Paper authors

- [Min Feng](https://scholariq.org/researchers/min-feng/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)

## Paper topics

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)
- [Cancer Research and Treatments](https://scholariq.org/topics/cancer-research-and-treatments/)
- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)

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