# <i>BRCA</i> Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/i-brca-i-reversion-mutations-in-circulating-tumor-dna-predict-primary-and/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Kevin Lin,Maria I. Harrell,Amit M. Oza,Ana Oaknin,Isabelle Ray‐Coquard,Anna V. Tinker,Elena Helman,Marc R. Radke,Carmen Say,Lan-Thanh Vo,Elaina Mann,Jeffrey D. Isaacson,Lara Maloney,David M. O’Malley,Setsuko K. Chambers,Scott H. Kaufmann,Clare L. Scott,Gottfried E. Konecny,Robert L. Coleman,James Sun,Heidi Giordano,James D. Brenton,Thomas C. Harding,Iain A. McNeish,Elizabeth M. Swisher |
| Citations | 439 |
| DOI | 10.1158/2159-8290.cd-18-0715 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2901506506 |
| PMID | 30425037 |
| Type | article |
| Year | 2018 |

## Paper authors

- [Amit M. Oza](https://scholariq.org/researchers/amit-m-oza/)
- [Robert L. Coleman](https://scholariq.org/researchers/robert-l-coleman/)
- [David M. O’Malley](https://scholariq.org/researchers/david-m-o-malley/)
- [Elizabeth M. Swisher](https://scholariq.org/researchers/elizabeth-m-swisher/)

## Paper journal

- [Cancer Discovery](https://scholariq.org/journals/cancer-discovery/)

## Paper primary topic

- [PARP inhibition in cancer therapy](https://scholariq.org/topics/parp-inhibition-in-cancer-therapy/)

## Paper topics

- [PARP inhibition in cancer therapy](https://scholariq.org/topics/parp-inhibition-in-cancer-therapy/)
- [Ovarian cancer diagnosis and treatment](https://scholariq.org/topics/ovarian-cancer-diagnosis-and-treatment/)
- [BRCA gene mutations in cancer](https://scholariq.org/topics/brca-gene-mutations-in-cancer/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.