# <i>miR-449a</i> and <i>miR-449b</i> are direct transcriptional targets of E2F1 and negatively regulate pRb–E2F1 activity through a feedback loop by targeting <i>CDK6</i> and <i>CDC25A</i>

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/i-mir-449a-i-and-i-mir-449b-i-are-direct-transcriptional-targets-of-e2f1-and/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Xiaojing Yang,Min Feng,Xia Jiang,Zhenlong Wu,Zhimei Li,Meiyee Aau,Qiang Yu |
| Citations | 247 |
| DOI | 10.1101/gad.1819009 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | true |
| OA Status | diamond |
| OA URL | http://genesdev.cshlp.org/content/23/20/2388.full.pdf |
| OpenAlex ID | https://openalex.org/W2014510815 |
| PMID | 19833767 |
| Type | preprint |
| Year | 2009 |

## Paper authors

- [Min Feng](https://scholariq.org/researchers/min-feng/)

## Paper primary topic

- [MicroRNA in disease regulation](https://scholariq.org/topics/microrna-in-disease-regulation/)

## Paper topics

- [MicroRNA in disease regulation](https://scholariq.org/topics/microrna-in-disease-regulation/)
- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)
- [RNA modifications and cancer](https://scholariq.org/topics/rna-modifications-and-cancer/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.