# Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/immune-checkpoint-tim-3-regulates-microglia-and-alzheimer-s-disease/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Kimitoshi Kimura,Ayshwarya Subramanian,Zhuoran Yin,Ahad Khalilnezhad,Yufan Wu,Danyang He,Karen O. Dixon,Udbhav K. Chitta,Xiaokai Ding,Niraj Adhikari,Isabell Guzchenko,Xiaoming Zhang,Ruihan Tang,Thomas Pertel,Samuel A. Myers,Aastha Aastha,Masashi Nomura,Ghazaleh Eskandari‐Sedighi,Vasundhara Singh,Lei Liu,Conner Lambden,Kilian Kleemann,Neha Gupta,Jen‐Li Barry,Ana Durao,Yiran Cheng,Sebastian Silveira,Huiyuan Zhang,Aamir Suhail,Toni Delorey,Orit Rozenblatt–Rosen,Gordon J. Freeman,Dennis J. Selkoe,Howard L. Weiner,Mathew Blurton‐Jones,Carlos Cruchaga,Aviv Regev,Mario L. Suvà,Oleg Butovsky,Vijay K. Kuchroo |
| Citations | 67 |
| DOI | 10.1038/s41586-025-08852-z |
| Fields | Immunology and Microbiology,Neuroscience |
| Open Access | true |
| OA Status | green |
| OA URL | https://pmc.ncbi.nlm.nih.gov/articles/PMC12079183/ |
| OpenAlex ID | https://openalex.org/W4409283791 |
| PMID | 40205047 |
| Type | article |
| Year | 2025 |

## Paper authors

- [Xiaokai Ding](https://scholariq.org/researchers/xiaokai-ding/)

## Paper journal

- [Nature](https://scholariq.org/journals/nature/)

## Paper primary topic

- [Neuroinflammation and Neurodegeneration Mechanisms](https://scholariq.org/topics/neuroinflammation-and-neurodegeneration-mechanisms/)

## Paper topics

- [Neuroinflammation and Neurodegeneration Mechanisms](https://scholariq.org/topics/neuroinflammation-and-neurodegeneration-mechanisms/)
- [Immune cells in cancer](https://scholariq.org/topics/immune-cells-in-cancer/)
- [Galectins and Cancer Biology](https://scholariq.org/topics/galectins-and-cancer-biology/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.