# Improvement of antimalarial activity of a 3-alkylpiridine alkaloid analog by replacing the pyridine ring to a thiazole-containing heterocycle: Mode of action, mutagenicity profile, and Caco-2 cell-based permeability

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/improvement-of-antimalarial-activity-of-a-3-alkylpiridine-alkaloid-analog-by/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Daniel Silqueira Martins Guimarães,Letícia Silveira de Sousa Luz,Sara Batista do Nascimento,Lorena Rabelo Silva,Natália Rezende de Miranda Martins,Heloísa Gonçalves de Almeida,Vitória de Souza Reis,Sarah El Chamy Maluf,Alexandre Budu,Juliane Aparecida Marinho,Clarice Abramo,Adriana K. Carmona,Marina Goulart da Silva,Gisele Rodrigues da Silva,Victor Matheus Kemmer,Anna Paola Butera,Renato Ribeiro-Viana,Marcos L. Gazarini,Clébio Soares Nascimento Júnior,Luciana Guimarães,Fábio Vieira dos Santos,Whocely Victor de Castro,Gustavo Henrique Ribeiro Viana,Cristiana Ferreira Alves de Brito,Fernando de Pilla Varotti |
| Citations | 15 |
| DOI | 10.1016/j.ejps.2019.105015 |
| Fields | Biochemistry, Genetics and Molecular Biology,Chemistry |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2963036853 |
| PMID | 31344442 |
| Type | article |
| Year | 2019 |

## Paper authors

- [Marina Goulart da Silva](https://scholariq.org/researchers/marina-goulart-da-silva/)

## Paper journal

- [European Journal of Pharmaceutical Sciences](https://scholariq.org/journals/european-journal-of-pharmaceutical-sciences/)

## Paper primary topic

- [Biochemistry, Genetics and Molecular Biology](https://scholariq.org/topics/biochemistry-genetics-and-molecular-biology/)

## Paper topics

- [Phenothiazines and Benzothiazines Synthesis and Activities](https://scholariq.org/topics/phenothiazines-and-benzothiazines-synthesis-and-activities/)
- [Synthesis and biological activity](https://scholariq.org/topics/synthesis-and-biological-activity/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.