# Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/inactivation-of-pnkp-by-mutant-atxn3-triggers-apoptosis-by-activating-the-dna/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Rui Gao,Yongping Liu,Anabela Silva‐Fernandes,Xiang Fang,Adriana Paulucci-Holthauzen,Arpita Chatterjee,Hang L. Zhang,Tohru Matsuura,Sanjeev Choudhary,Tetsuo Ashizawa,Arnulf H. Koeppen,Patrı́cia Maciel,Tapas K. Hazra,Partha S. Sarkar |
| Citations | 86 |
| DOI | 10.1371/journal.pgen.1004834 |
| Fields | Biochemistry, Genetics and Molecular Biology,Neuroscience |
| Open Access | true |
| OA Status | gold |
| OA URL | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004834&type=printable |
| OpenAlex ID | https://openalex.org/W1991915850 |
| PMID | 25590633 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Yongping Liu](https://scholariq.org/researchers/yongping-liu/)

## Paper primary topic

- [Genetic Neurodegenerative Diseases](https://scholariq.org/topics/genetic-neurodegenerative-diseases/)

## Paper topics

- [Genetic Neurodegenerative Diseases](https://scholariq.org/topics/genetic-neurodegenerative-diseases/)
- [DNA Repair Mechanisms](https://scholariq.org/topics/dna-repair-mechanisms/)
- [Mitochondrial Function and Pathology](https://scholariq.org/topics/mitochondrial-function-and-pathology/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.