# Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/inactivation-of-the-dna-repair-gene-o6-methylguanine-dna-methyltransferase-by/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Manel Esteller,M Toyota,Montse Sánchez‐Céspedes,Gabriel Capellá,Miguel A. Peinado,D. Neil Watkins,Jean‐Pierre J. Issa,David Sidransky,S B Baylin,James G. Herman |
| Citations | 543 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2137180582 |
| PMID | 10811111 |
| Type | article |
| Year | 2000 |

## Paper authors

- [Gabriel Capellá](https://scholariq.org/researchers/gabriel-capella/)
- [Montse Sánchez‐Céspedes](https://scholariq.org/researchers/montse-sanchez-cespedes/)
- [David Sidransky](https://scholariq.org/researchers/david-sidransky/)

## Paper journal

- [PubMed](https://scholariq.org/journals/pubmed/)

## Paper primary topic

- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)

## Paper topics

- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)
- [Cancer Genomics and Diagnostics](https://scholariq.org/topics/cancer-genomics-and-diagnostics/)
- [Genetic factors in colorectal cancer](https://scholariq.org/topics/genetic-factors-in-colorectal-cancer/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.