# Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/increased-hydrophobic-interactions-of-iclaprim-with-staphylococcus-aureus/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Christian Oefner,M. Bandera,Andreas Haldimann,Heike Laue,Henk Schulz,Seema Mukhija,Salvatore Parisi,L. Weiss,Sergio Lociuro,Glenn E. Dale |
| Citations | 106 |
| DOI | 10.1093/jac/dkp024 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2134443476 |
| PMID | 19211577 |
| Type | article |
| Year | 2009 |

## Paper authors

- [Andreas Haldimann](https://scholariq.org/researchers/andreas-haldimann/)

## Paper primary topic

- [Antimicrobial Resistance in Staphylococcus](https://scholariq.org/topics/antimicrobial-resistance-in-staphylococcus/)

## Paper topics

- [Antimicrobial Resistance in Staphylococcus](https://scholariq.org/topics/antimicrobial-resistance-in-staphylococcus/)
- [Antibiotic Resistance in Bacteria](https://scholariq.org/topics/antibiotic-resistance-in-bacteria/)
- [Antibiotic Use and Resistance](https://scholariq.org/topics/antibiotic-use-and-resistance/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.