# Induction of Apoptosis by Shikonin through Coordinative Modulation of the Bcl-2 Family, p27, and p53, Release of Cytochrome <i>c</i>, and Sequential Activation of Caspases in Human Colorectal Carcinoma Cells

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/induction-of-apoptosis-by-shikonin-through-coordinative-modulation-of-the-bcl-2/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Ping‐Chi Hsu,Yu‐Ting Huang,Mei‐Ling Tsai,Ying‐Jan Wang,Jen‐Kun Lin,Min‐Hsiung Pan |
| Citations | 108 |
| DOI | 10.1021/jf0495993 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine,Pharmacology, Toxicology and Pharmaceutics |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2006944445 |
| PMID | 15453709 |
| Type | article |
| Year | 2004 |

## Paper authors

- [Yu‐Ting Huang](https://scholariq.org/researchers/yu-ting-huang/)

## Paper primary topic

- [Bioactive Compounds and Antitumor Agents](https://scholariq.org/topics/bioactive-compounds-and-antitumor-agents/)

## Paper topics

- [Bioactive Compounds and Antitumor Agents](https://scholariq.org/topics/bioactive-compounds-and-antitumor-agents/)
- [Cell death mechanisms and regulation](https://scholariq.org/topics/cell-death-mechanisms-and-regulation/)
- [Cancer-related Molecular Pathways](https://scholariq.org/topics/cancer-related-molecular-pathways/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.