# Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinoma

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/integrated-multi-omics-characterization-reveals-a-distinctive-metabolic/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Giuseppe Lucarelli,Monica Rutigliano,Fabio Sallustio,Doménico Ribatti,Andrea Giglio,Martina Lepore Signorile,Valentina Grossi,Paola Sanese,Anna Napoli,Eugenio Maiorano,Cristina Bianchi,R Perego,Matteo Ferro,Elena Ranieri,Grazia Serino,Lauren N. Bell,Pasquale Ditonno,Cristiano Simone,Michele Battaglia |
| Citations | 250 |
| DOI | 10.18632/aging.101685 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | http://hdl.handle.net/10281/213399 |
| OpenAlex ID | https://openalex.org/W2904346214 |
| PMID | 30538212 |
| Type | article |
| Year | 2018 |

## Paper authors

- [Fabio Sallustio](https://scholariq.org/researchers/fabio-sallustio/)

## Paper primary topic

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)

## Paper topics

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)
- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)
- [Renal cell carcinoma treatment](https://scholariq.org/topics/renal-cell-carcinoma-treatment/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.