# JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/jak-inhibition-alleviates-the-cellular-senescence-associated-secretory-phenotype/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Ming Xu,Tamar Tchkonia,Husheng Ding,Mikołaj Ogrodnik,Ellen R. Lubbers,Tamar Pirtskhalava,Thomas A. White,Kurt O. Johnson,Michael B. Stout,Vojtěch Mezera,Nino Giorgadze,Michael D. Jensen,Nathan K. LeBrasseur,James L. Kirkland |
| Citations | 910 |
| DOI | 10.1073/pnas.1515386112 |
| Fields | Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://www.pnas.org/content/pnas/112/46/E6301.full.pdf |
| OpenAlex ID | https://openalex.org/W1932046626 |
| PMID | 26578790 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Ming Xu](https://scholariq.org/researchers/ming-xu-2/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [Neutrophil, Myeloperoxidase and Oxidative Mechanisms](https://scholariq.org/topics/neutrophil-myeloperoxidase-and-oxidative-mechanisms/)

## Paper topics

- [Neutrophil, Myeloperoxidase and Oxidative Mechanisms](https://scholariq.org/topics/neutrophil-myeloperoxidase-and-oxidative-mechanisms/)
- [IL-33, ST2, and ILC Pathways](https://scholariq.org/topics/il-33-st2-and-ilc-pathways/)
- [Telomeres, Telomerase, and Senescence](https://scholariq.org/topics/telomeres-telomerase-and-senescence/)

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