# Kidney-Targeted Birt-Hogg-Dube Gene Inactivation in a Mouse Model: Erk1/2 and Akt-mTOR Activation, Cell Hyperproliferation, and Polycystic Kidneys

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/kidney-targeted-birt-hogg-dube-gene-inactivation-in-a-mouse-model-erk1-2-and-akt/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Masaya Baba,M Furihata,Seung‐Beom Hong,Lino Tessarollo,Diana C. Haines,Eileen Southon,Vishal Patel,Peter Igarashi,W. Gregory Alvord,Robert M. Leighty,Masahiro Yao,Marcelino Bernardo,Lilia Ileva,Peter L. Choyke,Michelle B. Warren,Berton Zbar,W. Marston Linehan,Laura S. Schmidt |
| Citations | 259 |
| DOI | 10.1093/jnci/djm288 |
| Fields | Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://academic.oup.com/jnci/article-pdf/100/2/140/7682772/djm288.pdf |
| OpenAlex ID | https://openalex.org/W2170486847 |
| PMID | 18182616 |
| Type | article |
| Year | 2008 |

## Paper authors

- [Masahiro Yao](https://scholariq.org/researchers/masahiro-yao/)

## Paper journal

- [JNCI Journal of the National Cancer Institute](https://scholariq.org/journals/jnci-journal-of-the-national-cancer-institute/)

## Paper primary topic

- [Renal cell carcinoma treatment](https://scholariq.org/topics/renal-cell-carcinoma-treatment/)

## Paper topics

- [Renal cell carcinoma treatment](https://scholariq.org/topics/renal-cell-carcinoma-treatment/)
- [Tuberous Sclerosis Complex Research](https://scholariq.org/topics/tuberous-sclerosis-complex-research/)
- [Chemotherapy-induced organ toxicity mitigation](https://scholariq.org/topics/chemotherapy-induced-organ-toxicity-mitigation/)

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