# KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/klhl22-activates-amino-acid-dependent-mtorc1-signalling-to-promote-tumorigenesis/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jie Chen,Yuhui Ou,Yanyan Yang,Wen Li,Ye Xu,Yuntao Xie,Ying Liu |
| Citations | 129 |
| DOI | 10.1038/s41586-018-0128-9 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2803254364 |
| PMID | 29769719 |
| Type | article |
| Year | 2018 |

## Paper authors

- [Ye Xu](https://scholariq.org/researchers/ye-xu/)

## Paper journal

- [Nature](https://scholariq.org/journals/nature/)

## Paper primary topic

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

## Paper topics

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Ubiquitin and proteasome pathways](https://scholariq.org/topics/ubiquitin-and-proteasome-pathways/)
- [Histone Deacetylase Inhibitors Research](https://scholariq.org/topics/histone-deacetylase-inhibitors-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.