# Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/kupffer-cell-derived-tnf-triggers-cholangiocellular-tumorigenesis-through-jnk/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Detian Yuan,Shan Huang,Emanuel Berger,Lei Liu,Nina Groß,Florian Heinzmann,Marc Ringelhan,Tracy O. Connor,Mira Stadler,Michael T. Meister,Julia Weber,Rupert Öllinger,Nicole Simonavicius,Florian Reisinger,Daniel Hartmann,Rüdiger Meyer,Maria Reich,Marco Seehawer,Valentina Leone,Bastian Höchst,Dirk Wohlleber,Simone Jörs,Marco Prinz,Duncan Spalding,Ulrike Protzer,Tom Luedde,Luigi Terracciano,Matthias S. Matter,Thomas Longerich,Percy A. Knolle,Thomas Ried,Verena Keitel,Fabian Geisler,Kristian Unger,Einat Cinnamon,Eli Pikarsky,Norbert Hüser,Roger J. Davis,Darjus F. Tschaharganeh,Roland Rad,Achim Weber,Lars Zender,Dirk Haller,Mathias Heikenwälder |
| Citations | 196 |
| DOI | 10.1016/j.ccell.2017.05.006 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/7909318 |
| OpenAlex ID | https://openalex.org/W2626552234 |
| PMID | 28609656 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Marc Ringelhan](https://scholariq.org/researchers/marc-ringelhan/)

## Paper primary topic

- [Cholangiocarcinoma and Gallbladder Cancer Studies](https://scholariq.org/topics/cholangiocarcinoma-and-gallbladder-cancer-studies/)

## Paper topics

- [Cholangiocarcinoma and Gallbladder Cancer Studies](https://scholariq.org/topics/cholangiocarcinoma-and-gallbladder-cancer-studies/)
- [MicroRNA in disease regulation](https://scholariq.org/topics/microrna-in-disease-regulation/)
- [Cancer-related molecular mechanisms research](https://scholariq.org/topics/cancer-related-molecular-mechanisms-research/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.