# Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/long-term-safety-and-tolerability-of-prosavin-a-lentiviral-vector-based-gene/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Stéphane Palfi,Jean Marc Gurruchaga,G. Ralph,H. Lepetit,Sonia Lavisse,Philip C. Buttery,Colin Watts,James Miskin,Michelle Kelleher,Sarah Deeley,Hirokazu Iwamuro,Jean Pascal Lefaucheur,Claire Thiriez,Gilles Fénelon,Cherry Lucas,Pierre Brugières,Inanna Gabriel,K Abhay,Xavier Drouot,Naoki Tani,Aurélie Kas,Bijan Ghaleh,Philippe Le Corvoisier,Patrice Dolphin,David P Breen,Sarah Mason,Natalie Valle Guzman,Nicholas D. Mazarakis,Pippa A. Radcliffe,Richard Harrop,Susan M. Kingsman,Olivier Rascol,Stuart Naylor,Roger A. Barker,Philippe Hantraye,Philippe Rémy,Pierre Césaro,Kyriacos Mitrophanous |
| Citations | 438 |
| DOI | 10.1016/s0140-6736(13)61939-x |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine,Neuroscience |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2171214255 |
| PMID | 24412048 |
| Type | article |
| Year | 2014 |

## Paper authors

- [Xavier Drouot](https://scholariq.org/researchers/xavier-drouot/)

## Paper journal

- [The Lancet](https://scholariq.org/journals/the-lancet/)

## Paper primary topic

- [Virus-based gene therapy research](https://scholariq.org/topics/virus-based-gene-therapy-research/)

## Paper topics

- [Virus-based gene therapy research](https://scholariq.org/topics/virus-based-gene-therapy-research/)
- [Nerve injury and regeneration](https://scholariq.org/topics/nerve-injury-and-regeneration/)
- [Neurological disorders and treatments](https://scholariq.org/topics/neurological-disorders-and-treatments/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.