# Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/loss-of-function-nuclear-factor-b-subunit-1-nfkb1-variants-are-the-most-common/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Paul Tuijnenburg,Hana Lango Allen,Siobhan O. Burns,Daniel Greene,Machiel H. Jansen,Emily Staples,Jonathan Stephens,Keren Carss,Daniele Biasci,Helen Baxendale,Moira Thomas,Anita Chandra,Sorena Kiani‐Alikhan,Hilary Longhurst,Suranjith L. Seneviratne,Eric Oksenhendler,Ilenia Simeoni,Godelieve J. de Bree,Anton T. J. Tool,Ester M. M. van Leeuwen,Eduard H.T.M. Ebberink,Alexander B. Meijer,Salih Tuna,Deborah Whitehorn,Matthew A. Brown,Ernest Turro,Adrian J. Thrasher,Kenneth G. C. Smith,James Thaventhiran,Taco W. Kuijpers,Zoe Adhya,Hana Alachkar,Ariharan Anantharachagan,Richard Antrobus,Gururaj Arumugakani,Chiara Bacchelli,Helen Baxendale,Claire Bethune,Shahnaz Bibi,Barbara Boardman,Claire Booth,Michael J. Browning,Mary Brownlie,Siobhan O. Burns,Anita Chandra,Hayley Clifford,Nichola Cooper,Sophie Davies,John Dempster,Lisa Devlin,Rainer Döffinger,Elizabeth Drewe,David Edgar,William Egner,Tariq El‐Shanawany,Bobby Gaspar,Rohit Ghurye,Kimberley Gilmour,Sarah Goddard,Pavel Gordins,Sofia Grigoriadou,Scott Hackett,Rosie Hague,Lorraine Harper,Grant Hayman,Archana Herwadkar,Stephen Hughes,Aarnoud Huissoon,Stephen Jolles,Julie R. Jones,Peter Kelleher,Nigel Klein,Taco W. Kuijpers,Dinakantha Kumararatne,James Laffan,Hana Lango Allen,Sara Lear,Hilary Longhurst,Lorena Lorenzo,Jesmeen Maimaris,Ania Manson,Elizabeth McDermott,Hazel Millar,Anoop Mistry,Valerie Morrisson,Sai Murng,Iman Nasir,Sergey Nejentsev,Sadia Noorani,Éric Oksenhendler,Mark Ponsford,Waseem Qasim,Ellie Quinn,Isabella Quinti,Alex Richter,Crina Samarghitean,Ravishankar Sargur,Sinisa Savic,Suranjith L. Seneviratne,Carrock Sewall |
| Citations | 238 |
| DOI | 10.1016/j.jaci.2018.01.039 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology |
| Open Access | true |
| OA Status | hybrid |
| OA URL | http://www.jacionline.org/article/S0091674918302860/pdf |
| OpenAlex ID | https://openalex.org/W2792648208 |
| PMID | 29477724 |
| Type | article |
| Year | 2018 |

## Paper authors

- [Lisa Willcocks](https://scholariq.org/researchers/lisa-willcocks/)

## Paper journal

- [Journal of Allergy and Clinical Immunology](https://scholariq.org/journals/journal-of-allergy-and-clinical-immunology/)

## Paper primary topic

- [Immunodeficiency and Autoimmune Disorders](https://scholariq.org/topics/immunodeficiency-and-autoimmune-disorders/)

## Paper topics

- [Immunodeficiency and Autoimmune Disorders](https://scholariq.org/topics/immunodeficiency-and-autoimmune-disorders/)
- [NF-κB Signaling Pathways](https://scholariq.org/topics/nf-b-signaling-pathways/)
- [TGF-β signaling in diseases](https://scholariq.org/topics/tgf-signaling-in-diseases/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.