# Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/loss-of-jak2-regulation-via-a-heterodimeric-vhl-socs1-e3-ubiquitin-ligase/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Ryan C. Russell,Roxana I. Sufan,Bing Zhou,Pardeep Heir,Severa Bunda,Stephanie S. Sybingco,Samantha Greer,O. Roche,Samuel A. Heathcote,Vinca Chow,Lukasz M Boba,Terri D. Richmond,Michele M. Hickey,Dwayne L. Barber,David A. Cheresh,M. Celeste Simon,Meredith S. Irwin,William Y. Kim,Michael Ohh |
| Citations | 81 |
| DOI | 10.1038/nm.2370 |
| Fields | Immunology and Microbiology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2068094128 |
| PMID | 21685897 |
| Type | article |
| Year | 2011 |

## Paper authors

- [Bing Zhou](https://scholariq.org/researchers/bing-zhou/)

## Paper journal

- [Nature Medicine](https://scholariq.org/journals/nature-medicine/)

## Paper primary topic

- [Myeloproliferative Neoplasms: Diagnosis and Treatment](https://scholariq.org/topics/myeloproliferative-neoplasms-diagnosis-and-treatment/)

## Paper topics

- [Myeloproliferative Neoplasms: Diagnosis and Treatment](https://scholariq.org/topics/myeloproliferative-neoplasms-diagnosis-and-treatment/)
- [Cytokine Signaling Pathways and Interactions](https://scholariq.org/topics/cytokine-signaling-pathways-and-interactions/)
- [interferon and immune responses](https://scholariq.org/topics/interferon-and-immune-responses/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.