# M2 macrophage-derived extracellular vesicles facilitate CD8+T cell exhaustion in hepatocellular carcinoma via the miR-21-5p/YOD1/YAP/β-catenin pathway

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/m2-macrophage-derived-extracellular-vesicles-facilitate-cd8-t-cell-exhaustion-in/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jian Pu,Zuoming Xu,Jiahui Nian,Quan Fang,Meng Yang,Youguan Huang,Wenchuan Li,Bin Ge,Jianchu Wang,Huamei Wei |
| Citations | 112 |
| DOI | 10.1038/s41420-021-00556-3 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology |
| Open Access | true |
| OA Status | gold |
| OA URL | https://www.nature.com/articles/s41420-021-00556-3.pdf |
| OpenAlex ID | https://openalex.org/W3186014428 |
| PMID | 34282135 |
| Type | article |
| Year | 2021 |

## Paper authors

- [Jianchu Wang](https://scholariq.org/researchers/jianchu-wang/)

## Paper primary topic

- [Extracellular vesicles in disease](https://scholariq.org/topics/extracellular-vesicles-in-disease/)

## Paper topics

- [Extracellular vesicles in disease](https://scholariq.org/topics/extracellular-vesicles-in-disease/)
- [Immune cells in cancer](https://scholariq.org/topics/immune-cells-in-cancer/)
- [Phagocytosis and Immune Regulation](https://scholariq.org/topics/phagocytosis-and-immune-regulation/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.