# Metabolism of Tamoxifen by Recombinant Human Cytochrome P450 Enzymes: Formation of the 4-Hydroxy, 4′-Hydroxy and N-Desmethyl Metabolites and Isomerization of trans-4-Hydroxytamoxifen

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/metabolism-of-tamoxifen-by-recombinant-human-cytochrome-p450-enzymes-formation/

## Facts

| Field | Value |
| --- | --- |
| Author Names | H.K. Crewe,L. Notley,Rebecca M. Wunsch,M. S. Lennard,Elizabeth M. J. Gillam |
| Citations | 239 |
| DOI | 10.1124/dmd.30.8.869 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine,Pharmacology, Toxicology and Pharmaceutics |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2100073637 |
| PMID | 12124303 |
| Type | article |
| Year | 2002 |

## Paper authors

- [Elizabeth M. J. Gillam](https://scholariq.org/researchers/elizabeth-m-j-gillam/)

## Paper primary topic

- [Pharmacogenetics and Drug Metabolism](https://scholariq.org/topics/pharmacogenetics-and-drug-metabolism/)

## Paper topics

- [Pharmacogenetics and Drug Metabolism](https://scholariq.org/topics/pharmacogenetics-and-drug-metabolism/)
- [Estrogen and related hormone effects](https://scholariq.org/topics/estrogen-and-related-hormone-effects/)
- [Hormonal Regulation and Hypertension](https://scholariq.org/topics/hormonal-regulation-and-hypertension/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.