# Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/mild-hyperthermia-inhibits-homologous-recombination-induces-brca2-degradation/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Przemek M. Krawczyk,Berina Eppink,Jeroen Essers,Jan Stap,Hans M. Rodermond,Hanny Odijk,Alex N. Zelensky,Chris van Bree,Lukas J.A. Stalpers,Marrije R. Buist,Thomas Soullié,Joost A.P. Rens,Hence J.M. Verhagen,Mark J. O’Connor,Nicolaas A.P. Franken,Timo L.M. ten Hagen,Roland Kanaar,Jacob A. Aten |
| Citations | 344 |
| DOI | 10.1073/pnas.1101053108 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/3116433 |
| OpenAlex ID | https://openalex.org/W2162919209 |
| PMID | 21555554 |
| Type | article |
| Year | 2011 |

## Paper authors

- [Hence J.M. Verhagen](https://scholariq.org/researchers/hence-j-m-verhagen/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [PARP inhibition in cancer therapy](https://scholariq.org/topics/parp-inhibition-in-cancer-therapy/)

## Paper topics

- [PARP inhibition in cancer therapy](https://scholariq.org/topics/parp-inhibition-in-cancer-therapy/)
- [DNA Repair Mechanisms](https://scholariq.org/topics/dna-repair-mechanisms/)
- [Virus-based gene therapy research](https://scholariq.org/topics/virus-based-gene-therapy-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.