# Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in <i>ALK</i> -Rearranged Lung Cancer

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/molecular-mechanisms-of-resistance-to-first-and-second-generation-alk-inhibitors/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Justin F. Gainor,Leila Dardaei,Satoshi Yoda,Luc Friboulet,Ignaty Leshchiner,Ryohei Katayama,Ibiayi Dagogo‐Jack,Shirish M. Gadgeel,Katherine R. Schultz,Manrose Singh,Emily Chin,Melissa Parks,Dana Lee,Richard H. DiCecca,Elizabeth L. Lockerman,Tiffany G. Huynh,Jennifer Logan,Lauren L. Ritterhouse,Long P. Le,Ashok Muniappan,Subba R. Digumarthy,Colleen L. Channick,Colleen Keyes,Gad Getz,Dora Dias‐Santagata,Rebecca S. Heist,Jochen K. Lennerz,Lecia V. Sequist,Cyril H. Benes,A. John Iafrate,Mari Mino–Kenudson,Jeffrey A. Engelman,Alice T. Shaw |
| Citations | 1,157 |
| DOI | 10.1158/2159-8290.cd-16-0596 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/5050111 |
| OpenAlex ID | https://openalex.org/W2482427906 |
| PMID | 27432227 |
| Type | article |
| Year | 2016 |

## Paper authors

- [Justin F. Gainor](https://scholariq.org/researchers/justin-f-gainor/)
- [Jeffrey A. Engelman](https://scholariq.org/researchers/jeffrey-a-engelman/)
- [A. John Iafrate](https://scholariq.org/researchers/a-john-iafrate/)
- [Rebecca S. Heist](https://scholariq.org/researchers/rebecca-s-heist/)
- [Jochen K. Lennerz](https://scholariq.org/researchers/jochen-k-lennerz/)
- [Mari Mino–Kenudson](https://scholariq.org/researchers/mari-mino-kenudson/)
- [Lecia V. Sequist](https://scholariq.org/researchers/lecia-v-sequist/)
- [Alice T. Shaw](https://scholariq.org/researchers/alice-t-shaw/)

## Paper journal

- [Cancer Discovery](https://scholariq.org/journals/cancer-discovery/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [Lung Cancer Research Studies](https://scholariq.org/topics/lung-cancer-research-studies/)
- [Cancer therapeutics and mechanisms](https://scholariq.org/topics/cancer-therapeutics-and-mechanisms/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.