# Multicenter, 4-Week, Double-Blind, Randomized, Placebo-Controlled Trial of Lubiprostone, a Locally-Acting Type-2 Chloride Channel Activator, in Patients With Chronic Constipation

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/multicenter-4-week-double-blind-randomized-placebo-controlled-trial-of/

## Facts

| Field | Value |
| --- | --- |
| Author Names | John F. Johanson,Daniel Morton,Joseph E. Geenen,Ryuji Ueno |
| Citations | 333 |
| DOI | 10.1111/j.1572-0241.2007.01524.x |
| Fields | Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2041581988 |
| PMID | 17916109 |
| Type | article |
| Year | 2007 |

## Paper authors

- [Joseph E. Geenen](https://scholariq.org/researchers/joseph-e-geenen/)

## Paper journal

- [The American Journal of Gastroenterology](https://scholariq.org/journals/the-american-journal-of-gastroenterology/)

## Paper primary topic

- [Gastrointestinal motility and disorders](https://scholariq.org/topics/gastrointestinal-motility-and-disorders/)

## Paper topics

- [Gastrointestinal motility and disorders](https://scholariq.org/topics/gastrointestinal-motility-and-disorders/)
- [Gastroesophageal reflux and treatments](https://scholariq.org/topics/gastroesophageal-reflux-and-treatments/)
- [Migraine and Headache Studies](https://scholariq.org/topics/migraine-and-headache-studies/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.