# Multicenter, open-label, extension trial to evaluate the long-term efficacy and safety of early versus delayed treatment with tolvaptan in autosomal dominant polycystic kidney disease: the TEMPO 4:4 Trial

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/multicenter-open-label-extension-trial-to-evaluate-the-long-term-efficacy-and/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Vicente E. Torres,Arlene B. Chapman,Olivier Devuyst,Ron T. Gansevoort,Ronald D. Perrone,Ann Dandurand,John Ouyang,Frank S. Czerwiec,Jaime D. Blais,for the TEMPO 4:4 Trial Investigators |
| Citations | 182 |
| DOI | 10.1093/ndt/gfx043 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://academic.oup.com/ndt/article-pdf/33/3/477/25091570/gfx043.pdf |
| OpenAlex ID | https://openalex.org/W2604855121 |
| PMID | 28379536 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Vicente E. Torres](https://scholariq.org/researchers/vicente-e-torres/)
- [Jaime D. Blais](https://scholariq.org/researchers/jaime-d-blais/)
- [Ron T. Gansevoort](https://scholariq.org/researchers/ron-t-gansevoort/)
- [Frank S. Czerwiec](https://scholariq.org/researchers/frank-s-czerwiec/)
- [Olivier Devuyst](https://scholariq.org/researchers/olivier-devuyst/)
- [Ronald D. Perrone](https://scholariq.org/researchers/ronald-d-perrone/)
- [Arlene B. Chapman](https://scholariq.org/researchers/arlene-b-chapman/)

## Paper journal

- [Nephrology Dialysis Transplantation](https://scholariq.org/journals/nephrology-dialysis-transplantation/)

## Paper primary topic

- [Genetic and Kidney Cyst Diseases](https://scholariq.org/topics/genetic-and-kidney-cyst-diseases/)

## Paper topics

- [Genetic and Kidney Cyst Diseases](https://scholariq.org/topics/genetic-and-kidney-cyst-diseases/)
- [Renal Diseases and Glomerulopathies](https://scholariq.org/topics/renal-diseases-and-glomerulopathies/)
- [Complement system in diseases](https://scholariq.org/topics/complement-system-in-diseases/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.