# Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/mutations-in-brca1-and-brca2-differentially-affect-the-tumor-microenvironment/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Robert Samstein,Chirag Krishna,Xiaoxiao Ma,Xin Pei,Ken-Wing Lee,Vladimir Makarov,Fengshen Kuo,Jonathan Chung,Raghvendra M. Srivastava,Tanaya A. Purohit,Douglas R. Hoen,Rajarsi Mandal,Jeremy Setton,Wei Wu,Rachna Shah,Besnik Qeriqi,Qing Chang,Sviatoslav M. Kendall,Lior Z. Braunstein,Britta Weigelt,Pedro Blecua,Luc G.T. Morris,Diana Mandelker,Jorge S. Reis‐Filho,Elisa de Stanchina,Simon N. Powell,Timothy A. Chan,Nadeem Riaz |
| Citations | 216 |
| DOI | 10.1038/s43018-020-00139-8 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/8023400 |
| OpenAlex ID | https://openalex.org/W3106384965 |
| PMID | 33834176 |
| Type | article |
| Year | 2020 |

## Paper authors

- [Lior Z. Braunstein](https://scholariq.org/researchers/lior-z-braunstein/)
- [Jorge S. Reis‐Filho](https://scholariq.org/researchers/jorge-s-reis-filho/)

## Paper primary topic

- [Cancer Immunotherapy and Biomarkers](https://scholariq.org/topics/cancer-immunotherapy-and-biomarkers/)

## Paper topics

- [Cancer Immunotherapy and Biomarkers](https://scholariq.org/topics/cancer-immunotherapy-and-biomarkers/)
- [Cancer Genomics and Diagnostics](https://scholariq.org/topics/cancer-genomics-and-diagnostics/)
- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.