# Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/mutations-in-factor-h-reduce-binding-affinity-to-c3b-and-heparin-and-surface/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Tamara Manuelian,Jens Hellwage,Seppo Meri,Jessica Caprioli,Marina Noris,Stefan Heinen,Mihály Józsi,Hartmut P.H. Neumann,Giuseppe Remuzzi,Peter F. Zipfel |
| Citations | 342 |
| DOI | 10.1172/jci16651 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | http://www.jci.org/articles/view/16651/files/pdf |
| OpenAlex ID | https://openalex.org/W1965972308 |
| PMID | 12697737 |
| Type | article |
| Year | 2003 |

## Paper authors

- [Seppo Meri](https://scholariq.org/researchers/seppo-meri/)
- [Giuseppe Remuzzi](https://scholariq.org/researchers/giuseppe-remuzzi/)
- [Peter F. Zipfel](https://scholariq.org/researchers/peter-f-zipfel/)

## Paper primary topic

- [Complement system in diseases](https://scholariq.org/topics/complement-system-in-diseases/)

## Paper topics

- [Complement system in diseases](https://scholariq.org/topics/complement-system-in-diseases/)
- [Erythrocyte Function and Pathophysiology](https://scholariq.org/topics/erythrocyte-function-and-pathophysiology/)
- [Adenosine and Purinergic Signaling](https://scholariq.org/topics/adenosine-and-purinergic-signaling/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.