# Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/mutations-involved-in-aicardi-goutieres-syndrome-implicate-samhd1-as-regulator/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Gillian Rice,Jacquelyn Bond,Aruna Asipu,Rebecca Brunette,Iain W. Manfield,Ian Carr,Jonathan C. Fuller,Richard M. Jackson,Teresa M. Lamb,Tracy A. Briggs,Manir Ali,Hannah Gornall,Lydia R Couthard,Alec Aeby,Simon Attard-Montalto,Enrico Bertini,Christine Bodemer,Knut Brockmann,Louise Brueton,Peter Corry,Isabelle Desguerre,Elisa Fazzi,Àngels García Cazorla,Blanca Gener,Ben C.J. Hamel,Arvid Heiberg,Matthew F. Hunter,Marjo S. van der Knaap,Ram Kumar,Lieven Lagae,P. Landrieu,Charles Marques Lourenço,Daphna Marom,Michael McDermott,William van der Merwe,Simona Orcesi,Julie Prendiville,Magnhild Rasmussen,Stavit A. Shalev,Doriette Soler,Marwan Shinawi,Ronen Spiegel,Tiong Yang Tan,Adeline Vanderver,Emma Wakeling,Evangeline Wassmer,Elizabeth Whittaker,Pierre Lebon,Daniel B. Stetson,David T. Bonthron,Yanick J. Crow |
| Citations | 686 |
| DOI | 10.1038/ng.373 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2017760549 |
| PMID | 19525956 |
| Type | article |
| Year | 2009 |

## Paper authors

- [Lieven Lagae](https://scholariq.org/researchers/lieven-lagae/)

## Paper primary topic

- [interferon and immune responses](https://scholariq.org/topics/interferon-and-immune-responses/)

## Paper topics

- [interferon and immune responses](https://scholariq.org/topics/interferon-and-immune-responses/)
- [Inflammasome and immune disorders](https://scholariq.org/topics/inflammasome-and-immune-disorders/)
- [Systemic Lupus Erythematosus Research](https://scholariq.org/topics/systemic-lupus-erythematosus-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.