# Negative feedback–defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/negative-feedback-defective-prps1-mutants-drive-thiopurine-resistance-in/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Benshang Li,Hui Li,Yun Bai,Renate Kirschner‐Schwabe,Jun J. Yang,Yao Chen,Gang Lü,Gannie Tzoneva,Xiaotu Ma,Tongmin Wu,Wenjing Li,Haisong Lu,Lixia Ding,Huanhuan Liang,Xiaohang Huang,Minjun Yang,Lei Jin,Hui Kang,Shuting Chen,Alicia Le Du,Shuhong Shen,Jianping Ding,Hongzhuan Chen,Jing Chen,Arend von Stackelberg,Long-Jun Gu,Jinghui Zhang,Adolfo A. Ferrando,Jingyan Tang,Shengyue Wang,Bin‐Bing S. Zhou |
| Citations | 183 |
| DOI | 10.1038/nm.3840 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/4670083 |
| OpenAlex ID | https://openalex.org/W1921422688 |
| PMID | 25962120 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Huanhuan Liang](https://scholariq.org/researchers/huanhuan-liang/)
- [Lixia Ding](https://scholariq.org/researchers/lixia-ding/)

## Paper journal

- [Nature Medicine](https://scholariq.org/journals/nature-medicine/)

## Paper primary topic

- [Acute Lymphoblastic Leukemia research](https://scholariq.org/topics/acute-lymphoblastic-leukemia-research/)

## Paper topics

- [Acute Lymphoblastic Leukemia research](https://scholariq.org/topics/acute-lymphoblastic-leukemia-research/)
- [Biochemical and Molecular Research](https://scholariq.org/topics/biochemical-and-molecular-research/)
- [Viral-associated cancers and disorders](https://scholariq.org/topics/viral-associated-cancers-and-disorders/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.