# Novel Tacrine–Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/novel-tacrine-benzofuran-hybrids-as-potent-multitarget-directed-ligands-for-the/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Xiaoming Zha,Doriano Lamba,Lili Zhang,Yinghan Lou,Changxu Xu,Di Kang,Li Chen,Yungen Xu,Luyong Zhang,Angela De Simone,Sarah Samez,Alessandro Pesaresi,Jure Stojan,Manuela G. López,Javier Egea,Vincenza Andrisano,Manuela Bartolini |
| Citations | 130 |
| DOI | 10.1021/acs.jmedchem.5b01119 |
| Fields | Chemistry,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | http://hdl.handle.net/11585/550125 |
| OpenAlex ID | https://openalex.org/W2227380982 |
| PMID | 26632651 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Di Kang](https://scholariq.org/researchers/di-kang/)

## Paper primary topic

- [Cholinesterase and Neurodegenerative Diseases](https://scholariq.org/topics/cholinesterase-and-neurodegenerative-diseases/)

## Paper topics

- [Cholinesterase and Neurodegenerative Diseases](https://scholariq.org/topics/cholinesterase-and-neurodegenerative-diseases/)
- [Chemical synthesis and alkaloids](https://scholariq.org/topics/chemical-synthesis-and-alkaloids/)
- [Alzheimer's disease research and treatments](https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.