# Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/oral-advanced-glycation-endproducts-ages-promote-insulin-resistance-and-diabetes/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Weijing Cai,Maya Ramdas,Li Zhu,Xue Chen,Gary E. Striker,Helen Vlassara |
| Citations | 322 |
| DOI | 10.1073/pnas.1205847109 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://www.pnas.org/content/pnas/109/39/15888.full.pdf |
| OpenAlex ID | https://openalex.org/W2010036181 |
| PMID | 22908267 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Weijing Cai](https://scholariq.org/researchers/weijing-cai/)
- [Li Zhu](https://scholariq.org/researchers/li-zhu/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [Advanced Glycation End Products research](https://scholariq.org/topics/advanced-glycation-end-products-research/)

## Paper topics

- [Advanced Glycation End Products research](https://scholariq.org/topics/advanced-glycation-end-products-research/)
- [Natural Antidiabetic Agents Studies](https://scholariq.org/topics/natural-antidiabetic-agents-studies/)
- [Biochemical effects in animals](https://scholariq.org/topics/biochemical-effects-in-animals/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.