# Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/overcoming-acquired-resistance-to-letrozole-by-targeting-the-pi3k-akt-mtor/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Andrea Cavazzoni,Mara Bonelli,Claudia Fumarola,Silvia La Monica,Kinda Airoud,Ramona Bertoni,Roberta Alfieri,Maricla Galetti,Stefano Tramonti,Elena Galvani,Adrian L. Harris,Lesley-Ann Martin,Daniele Andreis,Alberto Bottini,Daniele Generali,Pier Giorgio Petronini |
| Citations | 88 |
| DOI | 10.1016/j.canlet.2012.03.034 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2102369206 |
| PMID | 22484466 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Silvia La Monica](https://scholariq.org/researchers/silvia-la-monica/)

## Paper primary topic

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

## Paper topics

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Estrogen and related hormone effects](https://scholariq.org/topics/estrogen-and-related-hormone-effects/)
- [Protein Kinase Regulation and GTPase Signaling](https://scholariq.org/topics/protein-kinase-regulation-and-gtpase-signaling/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.