# Pathway-based Rare Variant Burden Analysis Identifies a Role for the Complement System in an Extreme Phenotype of Sepsis with Coagulopathy

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/pathway-based-rare-variant-burden-analysis-identifies-a-role-for-the-complement/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Pavan K. Bendapudi,Sumaiya Nazeen,Justine Ryu,Onuralp Söylemez,Betty Rouaisnel,Meaghan Colling,Bryce Pasko,Alissa K. Robbins,Michael Bouzinier,Lindsay Tomczak,Lindsay Collier,Sanjay Ram,Ágnes Tóth-Petróczy,Joel B. Krier,Elizabeth L. Fieg,Sunny Dzik,James Hudspeth,Olga Pozdnyakova,Valentina Nardi,Richard L. Maas,Shamil Sunyaev,Julie-Aurore Losman |
| Citations | 2 |
| DOI | 10.1101/2022.02.24.22271459 |
| Fields | Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.medrxiv.org/content/medrxiv/early/2022/02/25/2022.02.24.22271459.full.pdf |
| OpenAlex ID | https://openalex.org/W4214680894 |
| Type | preprint |
| Year | 2022 |

## Paper authors

- [Bryce Pasko](https://scholariq.org/researchers/bryce-pasko/)

## Paper journal

- [medRxiv](https://scholariq.org/journals/medrxiv/)

## Paper primary topic

- [Complement system in diseases](https://scholariq.org/topics/complement-system-in-diseases/)

## Paper topics

- [Complement system in diseases](https://scholariq.org/topics/complement-system-in-diseases/)
- [Sepsis Diagnosis and Treatment](https://scholariq.org/topics/sepsis-diagnosis-and-treatment/)
- [Blood Coagulation and Thrombosis Mechanisms](https://scholariq.org/topics/blood-coagulation-and-thrombosis-mechanisms/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.