# PDK1 Signaling Toward PLK1–MYC Activation Confers Oncogenic Transformation, Tumor-Initiating Cell Activation, and Resistance to mTOR-Targeted Therapy

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/pdk1-signaling-toward-plk1-myc-activation-confers-oncogenic-transformation-tumor/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jing Tan,Zhimei Li,Puay Leng Lee,Peiyong Guan,Mei Yee Aau,Shuet Theng Lee,Min Feng,Cheryl Zihui Lim,Eric Yong Jing Lee,Zhen Ning Wee,Yaw Chyn Lim,R. Krishna Murthy Karuturi,Qiang Yu |
| Citations | 156 |
| DOI | 10.1158/2159-8290.cd-12-0595 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://cancerdiscovery.aacrjournals.org/content/candisc/3/10/1156.full.pdf |
| OpenAlex ID | https://openalex.org/W1999025078 |
| PMID | 23887393 |
| Type | article |
| Year | 2013 |

## Paper authors

- [Min Feng](https://scholariq.org/researchers/min-feng/)

## Paper journal

- [Cancer Discovery](https://scholariq.org/journals/cancer-discovery/)

## Paper primary topic

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

## Paper topics

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Microtubule and mitosis dynamics](https://scholariq.org/topics/microtubule-and-mitosis-dynamics/)
- [Cancer Cells and Metastasis](https://scholariq.org/topics/cancer-cells-and-metastasis/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.